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Full Length Chemically Modified Sgrna, supplied by Synthego Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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a The schematic shows the overall strategy of directed protein evolution by CRISPR base editor scanning and phenotypic selection OsTIR F74G to yield <t>a</t> <t>degron</t> system with minimal basal degradation, fast depletion kinetics, and faster target protein recovery. b The flow cytometry data show relative GFP reporter expression after various phenotypic selections. c The enrichment analysis shows relative sgRNA abundance in the S3 population compared to the parental cells. d The lollipop plots show variant frequencies of introduced mutations that overlap with the base editing window of the enriched <t>sgRNAs</t> in the S3 population compared to the parental cells.
Chemically Modified Sgrnas For Degron Ki Into Endogenous Genes, supplied by Synthego Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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a The schematic shows the overall strategy of directed protein evolution by CRISPR base editor scanning and phenotypic selection OsTIR F74G to yield <t>a</t> <t>degron</t> system with minimal basal degradation, fast depletion kinetics, and faster target protein recovery. b The flow cytometry data show relative GFP reporter expression after various phenotypic selections. c The enrichment analysis shows relative sgRNA abundance in the S3 population compared to the parental cells. d The lollipop plots show variant frequencies of introduced mutations that overlap with the base editing window of the enriched <t>sgRNAs</t> in the S3 population compared to the parental cells.
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chemically modified sgrna 205  (Synthego Inc)
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a The schematic shows the overall strategy of directed protein evolution by CRISPR base editor scanning and phenotypic selection OsTIR F74G to yield <t>a</t> <t>degron</t> system with minimal basal degradation, fast depletion kinetics, and faster target protein recovery. b The flow cytometry data show relative GFP reporter expression after various phenotypic selections. c The enrichment analysis shows relative sgRNA abundance in the S3 population compared to the parental cells. d The lollipop plots show variant frequencies of introduced mutations that overlap with the base editing window of the enriched <t>sgRNAs</t> in the S3 population compared to the parental cells.
Chemically Modified Sgrna 205, supplied by Synthego Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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chemically modified sgrna 205 - by Bioz Stars, 2026-06
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chemically modified sgrnas  (Synthego Inc)
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Synthego Inc chemically modified sgrnas
a The schematic shows the overall strategy of directed protein evolution by CRISPR base editor scanning and phenotypic selection OsTIR F74G to yield <t>a</t> <t>degron</t> system with minimal basal degradation, fast depletion kinetics, and faster target protein recovery. b The flow cytometry data show relative GFP reporter expression after various phenotypic selections. c The enrichment analysis shows relative sgRNA abundance in the S3 population compared to the parental cells. d The lollipop plots show variant frequencies of introduced mutations that overlap with the base editing window of the enriched <t>sgRNAs</t> in the S3 population compared to the parental cells.
Chemically Modified Sgrnas, supplied by Synthego Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/chemically modified sgrnas/product/Synthego Inc
Average 90 stars, based on 1 article reviews
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Synthego Inc chemically modified synthetic sgrnas
a The schematic shows the overall strategy of directed protein evolution by CRISPR base editor scanning and phenotypic selection OsTIR F74G to yield <t>a</t> <t>degron</t> system with minimal basal degradation, fast depletion kinetics, and faster target protein recovery. b The flow cytometry data show relative GFP reporter expression after various phenotypic selections. c The enrichment analysis shows relative sgRNA abundance in the S3 population compared to the parental cells. d The lollipop plots show variant frequencies of introduced mutations that overlap with the base editing window of the enriched <t>sgRNAs</t> in the S3 population compared to the parental cells.
Chemically Modified Synthetic Sgrnas, supplied by Synthego Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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chemically modified sgrna  (Synthego Inc)
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a The schematic shows the overall strategy of directed protein evolution by CRISPR base editor scanning and phenotypic selection OsTIR F74G to yield <t>a</t> <t>degron</t> system with minimal basal degradation, fast depletion kinetics, and faster target protein recovery. b The flow cytometry data show relative GFP reporter expression after various phenotypic selections. c The enrichment analysis shows relative sgRNA abundance in the S3 population compared to the parental cells. d The lollipop plots show variant frequencies of introduced mutations that overlap with the base editing window of the enriched <t>sgRNAs</t> in the S3 population compared to the parental cells.
Chemically Modified Sgrna, supplied by Synthego Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/chemically modified sgrna/product/Synthego Inc
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targeting synthetic chemically modified sgrnas  (Synthego Inc)
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a The schematic shows the overall strategy of directed protein evolution by CRISPR base editor scanning and phenotypic selection OsTIR F74G to yield <t>a</t> <t>degron</t> system with minimal basal degradation, fast depletion kinetics, and faster target protein recovery. b The flow cytometry data show relative GFP reporter expression after various phenotypic selections. c The enrichment analysis shows relative sgRNA abundance in the S3 population compared to the parental cells. d The lollipop plots show variant frequencies of introduced mutations that overlap with the base editing window of the enriched <t>sgRNAs</t> in the S3 population compared to the parental cells.
Targeting Synthetic Chemically Modified Sgrnas, supplied by Synthego Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Synthego Inc chemically modified sgrna ss151.mikbkap.g17
a The schematic shows the overall strategy of directed protein evolution by CRISPR base editor scanning and phenotypic selection OsTIR F74G to yield <t>a</t> <t>degron</t> system with minimal basal degradation, fast depletion kinetics, and faster target protein recovery. b The flow cytometry data show relative GFP reporter expression after various phenotypic selections. c The enrichment analysis shows relative sgRNA abundance in the S3 population compared to the parental cells. d The lollipop plots show variant frequencies of introduced mutations that overlap with the base editing window of the enriched <t>sgRNAs</t> in the S3 population compared to the parental cells.
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a The schematic shows the overall strategy of directed protein evolution by CRISPR base editor scanning and phenotypic selection OsTIR F74G to yield a degron system with minimal basal degradation, fast depletion kinetics, and faster target protein recovery. b The flow cytometry data show relative GFP reporter expression after various phenotypic selections. c The enrichment analysis shows relative sgRNA abundance in the S3 population compared to the parental cells. d The lollipop plots show variant frequencies of introduced mutations that overlap with the base editing window of the enriched sgRNAs in the S3 population compared to the parental cells.

Journal: Nature Communications

Article Title: Systematic comparison and base-editing-mediated directed protein evolution and functional screening yield superior auxin-inducible degron technology

doi: 10.1038/s41467-025-61848-1

Figure Lengend Snippet: a The schematic shows the overall strategy of directed protein evolution by CRISPR base editor scanning and phenotypic selection OsTIR F74G to yield a degron system with minimal basal degradation, fast depletion kinetics, and faster target protein recovery. b The flow cytometry data show relative GFP reporter expression after various phenotypic selections. c The enrichment analysis shows relative sgRNA abundance in the S3 population compared to the parental cells. d The lollipop plots show variant frequencies of introduced mutations that overlap with the base editing window of the enriched sgRNAs in the S3 population compared to the parental cells.

Article Snippet: Chemically modified sgRNAs for degron KI into endogenous genes were purchased from Synthego.

Techniques: CRISPR, Selection, Flow Cytometry, Expressing, Variant Assay